(Summing up)
Thanks for erudite remarks, I am overwhelmed and concerned. I will try to speak what I had in mind when I started this thread of discussion.
Buddhism:
The Suttas provide a framework of 4NT, N8P by which we humans make a progression from ignorance (avijja) generated plethora of existential sorrow in our current scenario (Vohara, Samutti, conventional reality) to bodhi (enlightenment), which is a complete resolution, par excellence, into an immeasurable junction (paramattha, supramundane) Nibbana.
Thus, the two Suttas are perfect guidance given by the Blessed One (the Buddha), we commence from avijja (ignorance) city and take the route of 4NT, N8P (aeroplane) and by attaining bodhi (enlightenment), ascend to the city of Nibbana.
• Kalama Sutta
Kalama Sutta can be considered as our current reference, the Buddha provides a guideline, unrelenting verifiability by self-reasoning, do not accept anything (superstition) by hearsay, be your own lamp. This is the abs genius of the Buddha.
Then the three generic evil roots of lust-hate-delusion (raga, dosa, moha) in the discourse delineate logical consequences. Take it, if it sounds good to the aspirant and see if it attenuates sorrow and promotes weal, else drop it and verify for yourself if it exacerbates sorrow.
• Khema Sutta
Fundamental enquiry into human condition, inherent insecurity whether we perish (zero, utter extinction) or continue (infinity, etetnity) after death is a deep discomfort triggered by existential sorrow. We are unable to connect the two.
Sister Khema provides the answer, a smart resolution that the progression into immeasurable and indescribable Nibbana is the summum bonum destination. The extremes, annihilation and eternity, are projections of the finite mind which grasps by measuring and describing, both are thus rejected.
Nibbana is achievable though immeasurable and indescribable.
Take it as a hypothesis and progressively verify.
(Like, ‘experiencing’ taste of honey is not measurable, immeasurable (subset), but achievable, one can experience the taste of honey. Nibbana is likewise reachable, though immeasurable and indescribabke, the finite experiencing the infinite. Of course, one has to work for it, 4NT, N8P).
Science:
Most of us humans are in Vohara (Conventional reality) with little awareness of Paramattha (Supramundane reality, Nibbana).
Mere rejection of Vohara will not lead to Paramattha. It can happen to a bhikkhu who is close to Sotapatti.
Thus Vohara needs careful addressing (Social order, Dhammacariya).
Science investigares a subset (samsara) of total reality (The Five Aggregates - rupa, vedana, sañña; samkhara, viññana), the methodology is sound (verifiability, Kalama Sutta) though the domain of enquiry is limited (primarily materiality-rupa). But Science has open frontiers (Kalama Sutta, be a lamp to yourself), theories change by verifiability.
Thus, Science is an appropriate tool to streamline human negotiation through existence (Vohara) by apt and ‘good’ technology (check epidemics, floods … attenuate existential suffering). However, the double edge sword of modern socio-economic-technology driven human organization is cunningly used by Mara and his army of devils to subvert ‘good’ by evil, progression of Dhamma by entropy disorder, crime, and wars.
Thus, it is not that Science has to be rejected for a smooth progression from avijja to bodhi.
Science could be very well supported by Buddhism to streamline Vohara, good social organization by equitability (The Buddha, Lord Jesus, Abraham Lincoln, gender equality, …) and tempered by holistic technology towards euphoria.
At the same time, it is urgent to focus on Paramattha which is the raison de etra of the Sangha.