Anymore? What would you consider different now than 2500 years ago? Or a million years ago? Existence is an inherently dangerous situation. To be born is literally to ascend in the direction of inevitable descent. That was always the way things would turn out. Unfortunately, due to the fact that information has a cumulative effect upon the impression that is “the world”, past and present are riddled with broken promises, baseless hopes, impossible dreams and seemingly endless possibilities, all taking for granted that sanctity from an external source was even possible.
So, while I respect your decision to see this situation as choiceless, it will always be the responsibility of the individual to make the effort to not depend external conditions for their composure or safety. What I think many people face in this contemporary world where that internal development of composure and virtue are deeply undervalued, is a “crisis of recognition” whereby they’ve spent a lifetime calculating precisely what they need from an external perspective in order to be happy, only to come face to face with the fact that it is nearly impossible to consistently generate that pleasing externality. With that, they seek information about how to go about altering how the external world, which they’ve already taken for granted as their only source of comfort, impacts their internal inclinations.
In short, it seems nowadays, in a world of one-click relief, that a person seeking a spiritual path has a few stages of realization to pass through prior to having the outlook that something like the Dhamma is even plausible. Where initially they may have felt entitled to a pleasant and fair external environment (and suffered deeply on account of it), they segue into finding a way to make that externality less painful, which is still nowhere near where the Dhamma would apply. From there, it takes a whole other shift for a person to consider, “Wait, what if it is my desires and preferences that is putting me in such painful opposition to circumstances?” That is right question, and with that attitude a person would cease to consider any relief as applicable to this new perspective. There is no longer a need to make the world more comfortable.
This scenario is timeless, though, but I do agree that nowadays it is far more complex. I just think any altering substance is nothing but that general depressurization of what is pressuring, and while that can be extraordinarily beautiful and comforting, it is not creating the conditions for the drying out the craving that drives the management of that pressure, and what a person is essentially doing by opting for that relief, is separating themselves from the responsibility that the eightfold path offers.
Reminds me of simile of the six murderer from SN 35.238, which was an intimate companion that supports you and keeps you safe only to kill you himself. Again, just be honest about your reasons for doing it so in the very least any misleading perspective will be immediately recognizable.